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Compound
PGDB_C024500
5 activity records1 related patents
2D structure
O=C1CCC(N2Cc3cc(NN4CCC5(CC4)CN(Cc4cnc(-c6ccccc6)cn4)C5)ccc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Inhibition | - | = | 60-70 | % | 0.5 uM | - | CRBN | CRBN | - | WO2025162225A1 | PGDB_A021181 | PGDB_C024500 | PGDB_AS002133 | View |
| % Inhibition | - | > | 30 | % | 0.1 uM | - | IKZF3 | - | - | WO2025162225A1 | PGDB_A031043 | PGDB_C024500 | PGDB_AS001902 | View |
| % Inhibition | - | = | 80-100 | % | 2 uM | - | CRBN | CRBN | - | WO2025162225A1 | PGDB_A066145 | PGDB_C024500 | PGDB_AS002540 | View |
| % Inhibition | - | = | 30-40 | % | 10 nM | 96 h | IKZF3 | - | MV-4-11 | WO2025162225A1 | PGDB_A074702 | PGDB_C024500 | PGDB_AS001155 | View |
| % Inhibition | - | = | 40-50 | % | 500 nM | 96 h | IKZF3 | - | MV-4-11 | WO2025162225A1 | PGDB_A075279 | PGDB_C024500 | PGDB_AS001561 | View |