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Compound
PGDB_C029781
10 activity records1 related patents
2D structure
COc1c(C#N)ccc(N2CC3(CCN(c4ccc(C(=O)N5CCC(CN6CCN7c8ccc(N9CCC(=O)NC9=O)cc8OCC[C@H]7C6)CC5)nn4)CC3)C[C@@H]2C)c1FCompound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 1.47 | nM | - | — | AR | - | VCaP | WO2026061104A1 | PGDB_A000666 | PGDB_C029781 | PGDB_AS000271 | View |
| % Degradation | - | = | 54 | % | 50 nM | - | AR | - | VCaP | WO2026061104A1 | PGDB_A004193 | PGDB_C029781 | PGDB_AS001838 | View |
| IC50 | - | = | 1.47 | nM | - | — | AR | - | VCaP | WO2026061104A1 | PGDB_A005923 | PGDB_C029781 | PGDB_AS000271 | View |
| % Degradation | - | = | 77 | % | 100 nM | - | AR | - | LNCaPFGC | WO2026061104A1 | PGDB_A078282 | PGDB_C029781 | PGDB_AS002389 | View |
| % Degradation | - | = | 45 | % | 10 nM | - | AR | - | LNCaPFGC | WO2026061104A1 | PGDB_A079602 | PGDB_C029781 | PGDB_AS002463 | View |
| % Degradation | - | = | 77 | % | 100 nM | - | AR | - | LNCaPFGC | WO2026061104A1 | PGDB_A079688 | PGDB_C029781 | PGDB_AS002389 | View |
| % Degradation | - | = | 54 | % | 50 nM | - | AR | - | VCaP | WO2026061104A1 | PGDB_A080002 | PGDB_C029781 | PGDB_AS001838 | View |
| % Degradation | - | = | 19 | % | 5 nM | - | AR | - | VCaP | WO2026061104A1 | PGDB_A080213 | PGDB_C029781 | PGDB_AS001354 | View |
| % Degradation | - | = | 19 | % | 5 nM | - | AR | - | VCaP | WO2026061104A1 | PGDB_A080259 | PGDB_C029781 | PGDB_AS001354 | View |
| % Degradation | - | = | 45 | % | 10 nM | - | AR | - | LNCaPFGC | WO2026061104A1 | PGDB_A081580 | PGDB_C029781 | PGDB_AS002463 | View |