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Compound
PGDB_C029853
6 activity records1 related patents
2D structure
COc1cc(N2CC3(CCN(c4ccc(C(=O)N5CCC(CN6CCN7c8ccc(C9CCC(=O)NC9=O)cc8OCC[C@H]7C6)CC5)c(F)c4)CC3)C[C@@H]2C)ccc1C#NCompound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | = | 59 | % | 5 nM | - | AR | - | VCaP | WO2026061104A1 | PGDB_A000694 | PGDB_C029853 | PGDB_AS001354 | View |
| IC50 | - | = | 0.008 | nM | - | — | AR | - | VCaP | WO2026061104A1 | PGDB_A000978 | PGDB_C029853 | PGDB_AS000271 | View |
| % Degradation | - | = | 61 | % | 10 nM | - | AR | - | LNCaPFGC | WO2026061104A1 | PGDB_A003663 | PGDB_C029853 | PGDB_AS002463 | View |
| % Degradation | - | = | 85 | % | 100 nM | - | AR | - | LNCaPFGC | WO2026061104A1 | PGDB_A005714 | PGDB_C029853 | PGDB_AS002389 | View |
| % Degradation | - | = | 73 | % | 50 nM | - | AR | - | VCaP | WO2026061104A1 | PGDB_A006000 | PGDB_C029853 | PGDB_AS001838 | View |
| IC50 | - | = | 0.32 | nM | - | — | AR | - | LNCaPFGC | WO2026061104A1 | PGDB_A079428 | PGDB_C029853 | PGDB_AS000195 | View |