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Compound
PGDB_C029925
6 activity records1 related patents
2D structure
Cc1cc(N2CCC3(CC2)C[C@H](C)N(c2ccc(C#N)c(Cl)c2)C3)ccc1C(=O)N1CCC(O[C@H]2CC[C@H](CN3CCN4c5ccc(N6CCC(=O)NC6=O)cc5OCC[C@H]4C3)CC2)CC1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 0.019 | nM | - | — | AR | - | VCaP | WO2026061104A1 | PGDB_A000527 | PGDB_C029925 | PGDB_AS000271 | View |
| IC50 | - | = | 0.23 | nM | - | — | AR | - | LNCaPFGC | WO2026061104A1 | PGDB_A000710 | PGDB_C029925 | PGDB_AS000195 | View |
| % Degradation | - | = | 90 | % | 100 nM | - | AR | - | LNCaPFGC | WO2026061104A1 | PGDB_A001034 | PGDB_C029925 | PGDB_AS002389 | View |
| % Degradation | - | = | 42 | % | 5 nM | - | AR | - | VCaP | WO2026061104A1 | PGDB_A001256 | PGDB_C029925 | PGDB_AS001354 | View |
| % Degradation | - | = | 80 | % | 50 nM | - | AR | - | VCaP | WO2026061104A1 | PGDB_A002396 | PGDB_C029925 | PGDB_AS001838 | View |
| % Degradation | - | = | 48 | % | 10 nM | - | AR | - | LNCaPFGC | WO2026061104A1 | PGDB_A003754 | PGDB_C029925 | PGDB_AS002463 | View |