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Compound
PGDB_C030052
6 activity records1 related patents
2D structure
CC1(CN2CCN3c4ccc(N5CCC(=O)NC5=O)cc4OCC[C@H]3C2)CCN(C(=O)c2ccc(N3CCC4(CC3)C[C@H](C(F)(F)F)N(c3ccc(C#N)c(Cl)c3)C4)cc2)CC1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 0.017 | nM | - | — | AR | - | VCaP | WO2026061104A1 | PGDB_A000218 | PGDB_C030052 | PGDB_AS000271 | View |
| IC50 | - | = | 0.28 | nM | - | — | AR | - | LNCaPFGC | WO2026061104A1 | PGDB_A001663 | PGDB_C030052 | PGDB_AS000195 | View |
| % Degradation | - | = | 64 | % | 5 nM | - | AR | - | VCaP | WO2026061104A1 | PGDB_A003494 | PGDB_C030052 | PGDB_AS001354 | View |
| % Degradation | - | = | 81 | % | 50 nM | - | AR | - | VCaP | WO2026061104A1 | PGDB_A004597 | PGDB_C030052 | PGDB_AS001838 | View |
| % Degradation | - | = | 14 | % | 10 nM | - | AR | - | LNCaPFGC | WO2026061104A1 | PGDB_A006533 | PGDB_C030052 | PGDB_AS002463 | View |
| % Degradation | - | = | 68 | % | 100 nM | - | AR | - | LNCaPFGC | WO2026061104A1 | PGDB_A080217 | PGDB_C030052 | PGDB_AS002389 | View |