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Compound
PGDB_C030099
6 activity records1 related patents
2D structure
C[C@H]1CC2(CCN(c3ccc(C(=O)N4CCC(C#N)(CN5CCN6c7ccc(N8CCC(=O)NC8=O)cc7OCC[C@H]6C5)CC4)nn3)CC2)CN1c1ccc(C#N)c(Cl)c1FCompound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 0.001 | nM | - | — | AR | - | VCaP | WO2026061104A1 | PGDB_A000614 | PGDB_C030099 | PGDB_AS000271 | View |
| IC50 | - | = | 1.4 | nM | - | — | AR | - | LNCaPFGC | WO2026061104A1 | PGDB_A002017 | PGDB_C030099 | PGDB_AS000195 | View |
| % Degradation | - | = | 74 | % | 10 nM | - | AR | - | LNCaPFGC | WO2026061104A1 | PGDB_A002228 | PGDB_C030099 | PGDB_AS002463 | View |
| % Degradation | - | = | 83 | % | 5 nM | - | AR | - | VCaP | WO2026061104A1 | PGDB_A004012 | PGDB_C030099 | PGDB_AS001354 | View |
| % Degradation | - | = | 87 | % | 50 nM | - | AR | - | VCaP | WO2026061104A1 | PGDB_A005712 | PGDB_C030099 | PGDB_AS001838 | View |
| % Degradation | - | = | 86 | % | 100 nM | - | AR | - | LNCaPFGC | WO2026061104A1 | PGDB_A006519 | PGDB_C030099 | PGDB_AS002389 | View |