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Compound
PGDB_C030313
11 activity records1 related patents
2D structure
Nc1nnc(-c2cc(F)ccc2O)cc1N1CC2CCC(C1)N2c1cccc(CN2CCN(Cc3ccc(N4CCC(=O)NC4=O)c(F)c3)CC2)c1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 100-200 | nM | - | — | - | - | H838 | WO2026061475A1 | PGDB_A000302 | PGDB_C030313 | PGDB_AS000282 | View |
| % Inhibition | - | = | 30-40 | % | 0.5 uM | - | CRBN | CRBN | - | WO2026061475A1 | PGDB_A004053 | PGDB_C030313 | PGDB_AS000662 | View |
| % Inhibition | - | = | 70-80 | % | 2 uM | - | CRBN | CRBN | - | WO2026061475A1 | PGDB_A004702 | PGDB_C030313 | PGDB_AS001031 | View |
| IC50 | - | = | 100-200 | nM | - | — | - | - | H1944 | WO2026061475A1 | PGDB_A005832 | PGDB_C030313 | PGDB_AS001924 | View |
| % Degradation | - | <= | 50 | % | Concentration series: 500 nM, 50 nM | - | SMARCA2 | - | MV-4-11 | WO2026061475A1 | PGDB_A080211 | PGDB_C030313 | PGDB_AS002335 | View |