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Compound
PGDB_C030340
11 activity records1 related patents
2D structure
Nc1nnc(-c2ccccc2O)cc1-c1cnn(C2CCC3(CC2)CN(Cc2cc(F)c4c(c2)CN(C2CCC(=O)NC2=O)C4=O)C3)c1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | <= | 50 | % | Concentration series: 500 nM, 50 nM | - | SMARCA4 | - | MV-4-11 | WO2026061475A1 | PGDB_A001048 | PGDB_C030340 | PGDB_AS002340 | View |
| % Inhibition | - | = | 60-70 | % | 2 uM | - | CRBN | CRBN | - | WO2026061475A1 | PGDB_A002128 | PGDB_C030340 | PGDB_AS001031 | View |
| % Inhibition | - | = | 10-20 | % | 0.5 uM | - | CRBN | CRBN | - | WO2026061475A1 | PGDB_A003912 | PGDB_C030340 | PGDB_AS000662 | View |
| % Degradation | - | <= | 50 | % | Concentration series: 500 nM, 50 nM | - | SMARCA2 | - | MV-4-11 | WO2026061475A1 | PGDB_A005304 | PGDB_C030340 | PGDB_AS002335 | View |
| IC50 | - | = | 1-5 | nM | - | — | - | - | H838 | WO2026061475A1 | PGDB_A079638 | PGDB_C030340 | PGDB_AS000282 | View |