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Compound
PGDB_C030362
9 activity records1 related patents
2D structure
Nc1nnc(-c2ccccc2O)cc1NC1CCN(Cc2cc(F)c3c(c2)CN(C2CCC(=O)NC2=O)C3=O)CC1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | <= | 1 | nM | - | — | - | - | A375 | WO2026061475A1 | PGDB_A000194 | PGDB_C030362 | PGDB_AS002441 | View |
| % Inhibition | - | = | 80-90 | % | 2 uM | - | CRBN | CRBN | - | WO2026061475A1 | PGDB_A001455 | PGDB_C030362 | PGDB_AS001031 | View |
| IC50 | - | = | 10-20 | nM | - | — | - | - | H1944 | WO2026061475A1 | PGDB_A005154 | PGDB_C030362 | PGDB_AS001924 | View |
| % Inhibition | - | = | 40-53 | % | 0.5 uM | - | CRBN | CRBN | - | WO2026061475A1 | PGDB_A081249 | PGDB_C030362 | PGDB_AS000662 | View |