PatGlueDB | Molecular Glue Patent Bioactivity Database

Patent summary

Publication numberCN120265631A

AssigneeShanghai Chaoyang Pharmaceutical

TitleQuinolinone compounds and naphthyridone compounds and uses thereof

Family ID91897771

Family members3

Filing year2024

Publication date2025-07-04

JurisdictionCN

Compounds94

Activity records150

Assays3

Activity compounds and values

Activity records

150 records

	Control		Value		Concentration	Time				Record ID	Compound	Assay	Details
IC50	-	=	0.4	nM	-	—	PDE3A	-	A2058	PGDB_A007087	PGDB_C007100	PGDB_AS000265	View
IC50	-	=	966.8	nM	-	—	PDE3A	-	-	PGDB_A007391	PGDB_C007066	PGDB_AS000140	View
IC50	-	=	9.7	nM	-	—	PDE3A	-	SK-MEL-3	PGDB_A007655	PGDB_C007106	PGDB_AS001659	View
IC50	-	=	0.4	nM	-	—	PDE3A	-	SK-MEL-3	PGDB_A007838	PGDB_C007104	PGDB_AS001659	View
IC50	-	=	31.9	nM	-	—	PDE3A	-	A2058	PGDB_A008152	PGDB_C007098	PGDB_AS000265	View
IC50	-	=	1.6	nM	-	—	PDE3A	-	SK-MEL-3	PGDB_A008379	PGDB_C007087	PGDB_AS001659	View
IC50	-	=	212.7	nM	-	—	PDE3A	-	-	PGDB_A008548	PGDB_C007106	PGDB_AS000140	View
IC50	-	=	5.2	nM	-	—	PDE3A	-	SK-MEL-3	PGDB_A009197	PGDB_C007144	PGDB_AS001659	View
IC50	-	=	5.2	nM	-	—	PDE3A	-	A2058	PGDB_A009242	PGDB_C007118	PGDB_AS000265	View
IC50	-	=	2.7	nM	-	—	PDE3A	-	A2058	PGDB_A009411	PGDB_C007108	PGDB_AS000265	View
IC50	-	=	1.1	nM	-	—	PDE3A	-	A2058	PGDB_A009917	PGDB_C007085	PGDB_AS000265	View
IC50	-	=	4.4	nM	-	—	PDE3A	-	SK-MEL-3	PGDB_A010257	PGDB_C007107	PGDB_AS001659	View
IC50	-	=	1125	nM	-	—	PDE3A	-	-	PGDB_A010313	PGDB_C007107	PGDB_AS000140	View
IC50	-	=	2.3	nM	-	—	PDE3A	-	SK-MEL-3	PGDB_A010687	PGDB_C007095	PGDB_AS001659	View
IC50	-	=	1.6	nM	-	—	PDE3A	-	SK-MEL-3	PGDB_A010688	PGDB_C007093	PGDB_AS001659	View
IC50	-	=	0.07	nM	-	—	PDE3A	-	SK-MEL-3	PGDB_A011374	PGDB_C007140	PGDB_AS001659	View
IC50	-	=	0.8	nM	-	—	PDE3A	-	SK-MEL-3	PGDB_A011933	PGDB_C007082	PGDB_AS001659	View
IC50	-	=	5.2	nM	-	—	PDE3A	-	A2058	PGDB_A012133	PGDB_C007119	PGDB_AS000265	View
IC50	-	=	2.5	nM	-	—	PDE3A	-	SK-MEL-3	PGDB_A012926	PGDB_C007115	PGDB_AS001659	View
IC50	-	=	1.1	nM	-	—	PDE3A	-	SK-MEL-3	PGDB_A013410	PGDB_C007112	PGDB_AS001659	View

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