PatGlueDB | Molecular Glue Patent Bioactivity Database

Patent summary

Publication numberCN120329284A

AssigneeShanghai Institute Of Organic Chemistry Of Cas

TitleCell cycle dependent kinase degrader and preparation method and use thereof

Family ID96364226

Family members2

Filing year2024

Publication date2025-07-18

JurisdictionCN

Compounds72

Activity records97

Assays4

Activity compounds and values

Activity records

97 records

	Control		Value		Concentration	Time				Record ID	Compound	Assay	Details
IC50	-	=	188	nM	-	—	CCNK	-	COV362	PGDB_A007569	PGDB_C006738	PGDB_AS002147	View
IC50	-	=	18	nM	-	—	CCNK	-	SK-OV-3	PGDB_A008720	PGDB_C007203	PGDB_AS001264	View
IC50	-	=	2	nM	-	—	CCNK	-	SK-OV-3	PGDB_A009641	PGDB_C007198	PGDB_AS001264	View
IC50	-	=	3	nM	-	—	CCNK	-	SK-OV-3	PGDB_A010324	PGDB_C007187	PGDB_AS001264	View
IC50	-	=	3	nM	-	—	CCNK	-	SK-OV-3	PGDB_A010753	PGDB_C007181	PGDB_AS001264	View
IC50	-	=	14	nM	-	—	CCNK	-	SK-OV-3	PGDB_A010789	PGDB_C007216	PGDB_AS001264	View
IC50	-	<	1	nM	-	—	CCNK	-	SK-OV-3	PGDB_A012189	PGDB_C007222	PGDB_AS001264	View
IC50	-	<	1	nM	-	—	CCNK	-	SK-OV-3	PGDB_A012759	PGDB_C007199	PGDB_AS001264	View
IC50	-	=	7	nM	-	—	CCNK	-	Jurkat	PGDB_A013073	PGDB_C007160	PGDB_AS002186	View
IC50	-	<	1	nM	-	—	CCNK	-	SK-OV-3	PGDB_A014668	PGDB_C007219	PGDB_AS001264	View
IC50	-	=	7	nM	-	—	CCNK	-	SK-OV-3	PGDB_A014788	PGDB_C007227	PGDB_AS001264	View
IC50	-	<	1	nM	-	—	CCNK	-	SK-OV-3	PGDB_A017667	PGDB_C007223	PGDB_AS001264	View
IC50	-	=	1	nM	-	—	CCNK	-	PA-1	PGDB_A018518	PGDB_C007161	PGDB_AS002297	View
IC50	-	=	11	nM	-	—	CCNK	-	Jurkat	PGDB_A019452	PGDB_C007162	PGDB_AS002186	View
IC50	-	=	18	nM	-	—	CCNK	-	SK-OV-3	PGDB_A020738	PGDB_C007203	PGDB_AS001264	View
IC50	-	<	1	nM	-	—	CCNK	-	SK-OV-3	PGDB_A020829	PGDB_C007228	PGDB_AS001264	View
IC50	-	=	4	nM	-	—	CCNK	-	SK-OV-3	PGDB_A021162	PGDB_C007179	PGDB_AS001264	View
IC50	-	=	2	nM	-	—	CCNK	-	SK-OV-3	PGDB_A021344	PGDB_C007168	PGDB_AS001264	View
IC50	-	<	1	nM	-	—	CCNK	-	SK-OV-3	PGDB_A021398	PGDB_C007226	PGDB_AS001264	View
IC50	-	=	81	nM	-	—	CCNK	-	SK-OV-3	PGDB_A021529	PGDB_C007205	PGDB_AS001264	View

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