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SIMM · NJU
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·
SIMM · NJU
Target
WEE1
4,708 activity records
2,388 compounds
13 patents
Target summary
Target ID
PGDB_T000046
Name
WEE1
Gene symbol
WEE1
Protein name
Wee1-like protein kinase
UniProt ID
P30291
Role
degradation_target | neo_substrate | primary_target
Compounds
2,388
Activity records
4,708
Assays
25
Patents
13
Activity compounds and values
Activity records
4,708 records
Structure
Metric
Control
Relation
Value
Unit
Concentration
Time
Target
E3
Cell line
Patent
Record ID
Compound
Assay
Details
IC50
-
<=
10
nM
-
—
WEE1
-
-
WO2026082160A1
PGDB_A006101
PGDB_C031167
PGDB_AS002113
View
EC50
-
=
0
uM
-
—
WEE1
-
293T-LentiXWEE1-ePL
WO2025137053A1
PGDB_A007011
PGDB_C011178
PGDB_AS001798
View
% Degradation
-
>=
0
%
Concentration series: 500 nM, 50 nM
24 h
WEE1
-
-
WO2025016359A1
PGDB_A007108
PGDB_C019321
PGDB_AS000593
View
Ymin
-
=
8.183127473
%
Concentration series: 1 uM, 10 uM
120 h
WEE1
-
MKN45
CN119325469A
PGDB_A007133
PGDB_C023462
PGDB_AS000567
View
EC50
-
=
0.001609494
uM
-
—
WEE1
-
MKN45
CN119325469A
PGDB_A007154
PGDB_C023390
PGDB_AS001345
View
EC50
-
=
0.065544
uM
-
—
WEE1
-
HEK293T
CN119325469A
PGDB_A007156
PGDB_C023181
PGDB_AS001487
View
% Degradation
-
=
68
%
Concentration range: 10 uM
4 h
WEE1
-
HEK293T
CN119325469A
PGDB_A007166
PGDB_C023371
PGDB_AS001384
View
% Degradation
-
>=
20
%
Concentration series: 500 nM, 50 nM
24 h
WEE1
-
-
WO2025016359A1
PGDB_A007180
PGDB_C019458
PGDB_AS000593
View
EC50
-
=
0.004
uM
-
—
WEE1
-
293T-LentiXWEE1-ePL
WO2025137053A1
PGDB_A007187
PGDB_C011214
PGDB_AS001798
View
EC50
-
=
0.114
uM
-
—
WEE1
-
MKN45
WO2026030657A1
PGDB_A007195
PGDB_C012484
PGDB_AS002574
View
Ymin
-
=
7.53
%
Concentration series: 1 uM, 10 uM
120 h
WEE1
-
MKN45
CN119325469A
PGDB_A007261
PGDB_C023368
PGDB_AS000567
View
% Degradation
-
=
65.80090714
%
Concentration range: 10 uM
4 h
WEE1
-
HEK293T
CN119325469A
PGDB_A007270
PGDB_C023519
PGDB_AS001384
View
Ymin
-
=
27.8
%
Concentration series: 1 uM, 10 uM
4 h
WEE1
-
293T-LentiXWEE1-ePL
WO2025137053A1
PGDB_A007294
PGDB_C011139
PGDB_AS001848
View
% Degradation
-
=
72.0959816
%
Concentration range: 10 uM
4 h
WEE1
-
HEK293T
CN119325469A
PGDB_A007297
PGDB_C023448
PGDB_AS001384
View
Ymin
-
=
8.59
%
Concentration series: 1 uM, 10 uM
120 h
WEE1
-
MKN45
CN119325469A
PGDB_A007360
PGDB_C023313
PGDB_AS000567
View
EC50
-
=
0.013813886
uM
-
—
WEE1
-
MKN45
CN119325469A
PGDB_A007383
PGDB_C023528
PGDB_AS001345
View
EC50
-
=
0.022697587
uM
-
—
WEE1
-
MKN45
CN119325469A
PGDB_A007420
PGDB_C023457
PGDB_AS001345
View
% Degradation
-
=
0-20
%
Concentration series: 500 nM, 50 nM
24 h
WEE1
-
-
CN120548310A
PGDB_A007469
PGDB_C000795
PGDB_AS001655
View
EC50
-
=
0.013077475
uM
-
—
WEE1
-
HEK293T
CN119325469A
PGDB_A007479
PGDB_C023457
PGDB_AS001487
View
EC50
-
=
0.004468
uM
-
—
WEE1
-
HEK293T
CN119325469A
PGDB_A007492
PGDB_C023150
PGDB_AS001487
View
