PatGlueDB | Molecular Glue Patent Bioactivity Database

Target summary

Target IDPGDB_T000056

NameSMARCA4

Gene symbolSMARCA4

Protein nameSWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4

UniProt IDP51532

Roledegradation_target | primary_target

Compounds1,158

Activity records2,588

Assays8

Patents5

Activity compounds and values

Activity records

2,588 records

	Control		Value		Concentration	Time					Record ID	Compound	Assay	Details
DC50	-	=	10000	nM	-	—	SMARCA4	-	Calu-6	WO2026128580A1	PGDB_A000005	PGDB_C032272	PGDB_AS001413	View
DC50	-	=	10000	nM	-	—	SMARCA4	-	Calu-6	WO2026128580A1	PGDB_A000008	PGDB_C032265	PGDB_AS001413	View
DC50	-	=	43.4	nM	-	—	SMARCA4	-	Calu-6	WO2026128580A1	PGDB_A000050	PGDB_C032365	PGDB_AS001413	View
% Degradation	-	<=	50	%	Concentration series: 500 nM, 50 nM	-	SMARCA4	-	MV-4-11	WO2026061475A1	PGDB_A000055	PGDB_C030482	PGDB_AS002340	View
% Degradation	-	<=	50	%	Concentration series: 500 nM, 50 nM	-	SMARCA4	-	MV-4-11	WO2026061475A1	PGDB_A000088	PGDB_C030603	PGDB_AS002340	View
Dmax	-	=	40.77	%	-	5 min	SMARCA4	-	Calu-6	WO2026128580A1	PGDB_A000110	PGDB_C032359	PGDB_AS002111	View
DC50	-	=	1000	nM	-	—	SMARCA4	-	Calu-6	WO2026128580A1	PGDB_A000113	PGDB_C032341	PGDB_AS001413	View
Dmax	-	=	33.51	%	-	5 min	SMARCA4	-	Calu-6	WO2026128580A1	PGDB_A000114	PGDB_C032361	PGDB_AS002111	View
% Degradation	-	<=	50	%	Concentration series: 500 nM, 50 nM	-	SMARCA4	-	MV-4-11	WO2026061475A1	PGDB_A000138	PGDB_C030407	PGDB_AS002340	View
DC50	-	=	1000	nM	-	—	SMARCA4	-	Calu-6	WO2026128580A1	PGDB_A000157	PGDB_C032404	PGDB_AS001413	View
Dmax	-	=	24.33	%	-	5 min	SMARCA4	-	Calu-6	WO2026128580A1	PGDB_A000172	PGDB_C032394	PGDB_AS002111	View
Dmax	-	=	49.51	%	-	5 min	SMARCA4	-	Calu-6	WO2026128580A1	PGDB_A000196	PGDB_C032398	PGDB_AS002111	View
Dmax	-	=	56.27	%	-	5 min	SMARCA4	-	Calu-6	WO2026128580A1	PGDB_A000204	PGDB_C032376	PGDB_AS002111	View
DC50	-	=	10000	nM	-	—	SMARCA4	-	Calu-6	WO2026128580A1	PGDB_A000238	PGDB_C032441	PGDB_AS001413	View
DC50	-	=	41.7	nM	-	—	SMARCA4	-	Calu-6	WO2026128580A1	PGDB_A000240	PGDB_C032325	PGDB_AS001413	View
DC50	-	=	1000	nM	-	—	SMARCA4	-	Calu-6	WO2026128580A1	PGDB_A000258	PGDB_C032357	PGDB_AS001413	View
% Degradation	-	<=	50	%	Concentration series: 500 nM, 50 nM	-	SMARCA4	-	MV-4-11	WO2026061475A1	PGDB_A000279	PGDB_C030397	PGDB_AS002340	View
Dmax	-	=	23.29	%	-	5 min	SMARCA4	-	Calu-6	WO2026128580A1	PGDB_A000306	PGDB_C032321	PGDB_AS002111	View
Dmax	-	=	15.01	%	-	5 min	SMARCA4	-	Calu-6	WO2026128580A1	PGDB_A000365	PGDB_C032349	PGDB_AS002111	View
DC50	-	=	10000	nM	-	—	SMARCA4	-	Calu-6	WO2026128580A1	PGDB_A000367	PGDB_C032337	PGDB_AS001413	View

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