Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C002535
5 activity records1 related patents
2D structure
O=C1CCC(N2Cc3c(ccc(CN4C5CC4CN(Cc4ccccc4-c4ccc(Cl)cc4)C5)c3F)C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | > | 50 | % | Concentration context: 500 nM | 24 h | GSPT1 | - | - | WO2024032689A1 | PGDB_A009150 | PGDB_C002535 | PGDB_AS000668 | View |
| % Degradation | - | > | 50 | % | Concentration context: 500 nM | 24 h | IKZF3 | - | - | WO2024032689A1 | PGDB_A016083 | PGDB_C002535 | PGDB_AS000176 | View |
| IC50 | - | = | 0.8 | uM | - | — | CRBN | CRBN | - | WO2024032689A1 | PGDB_A019455 | PGDB_C002535 | PGDB_AS000095 | View |
| % Degradation | - | < | 50 | % | Concentration context: 500 nM | 24 h | IKZF1 | - | - | WO2024032689A1 | PGDB_A050797 | PGDB_C002535 | PGDB_AS002239 | View |
| IC50 | - | = | 500-1000 | nM | - | — | - | - | Mino | WO2024032689A1 | PGDB_A062297 | PGDB_C002535 | PGDB_AS001319 | View |