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Compound
PGDB_C002572
4 activity records1 related patents
2D structure
CC1(C)CCC(CC2CC3CCC(C2)N3Cc2ccc3c(c2F)CN(C2CCC(=O)NC2=O)C3=O)=C(c2ccc(Cl)cc2)C1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | > | 50 | % | Concentration context: 500 nM | 24 h | IKZF3 | - | - | WO2024032689A1 | PGDB_A016956 | PGDB_C002572 | PGDB_AS000176 | View |
| IC50 | - | = | 0.51 | uM | - | — | CRBN | CRBN | - | WO2024032689A1 | PGDB_A041701 | PGDB_C002572 | PGDB_AS000095 | View |
| % Degradation | - | > | 50 | % | Concentration context: 500 nM | 24 h | GSPT1 | - | - | WO2024032689A1 | PGDB_A048446 | PGDB_C002572 | PGDB_AS000668 | View |
| % Degradation | - | < | 50 | % | Concentration context: 500 nM | 24 h | IKZF1 | - | - | WO2024032689A1 | PGDB_A055640 | PGDB_C002572 | PGDB_AS002239 | View |