Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C002576
4 activity records1 related patents
2D structure
CC1(C)CCC(CN2C[C@@H]3C[C@H]2CN3Cc2ccc3c(c2)CN(C2CCC(=O)NC2=O)C3=O)=C(c2ccc(Cl)cc2)C1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | > | 50 | % | Concentration context: 500 nM | 24 h | IKZF3 | - | - | WO2024032689A1 | PGDB_A013760 | PGDB_C002576 | PGDB_AS000176 | View |
| % Degradation | - | < | 50 | % | Concentration context: 500 nM | 24 h | GSPT1 | - | - | WO2024032689A1 | PGDB_A035777 | PGDB_C002576 | PGDB_AS000668 | View |
| IC50 | - | = | 0.77 | uM | - | — | CRBN | CRBN | - | WO2024032689A1 | PGDB_A055116 | PGDB_C002576 | PGDB_AS000095 | View |
| % Degradation | - | > | 50 | % | Concentration context: 500 nM | 24 h | IKZF1 | - | - | WO2024032689A1 | PGDB_A070630 | PGDB_C002576 | PGDB_AS002239 | View |