Assay

PGDB_AS000302

System: cell_basedTarget: IKZF1Cell line: Jurkat
Assay context summary

Assay context

339 activity records
Assay family% Degradation
Systemcell_based
ReadoutDC50
TargetIKZF1
E3Not specified
Cell lineJurkat
OrganismHomo sapiens
Technologyflow_cytometry
Detection targetprotein_degradation
Activity compounds and values

Activity records

339 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C030999
DC50-=92nM-—IKZF1-JurkatWO2026080794A1PGDB_A000023PGDB_C030999PGDB_AS000302View
2D structure for PGDB_C030912
DC50-=1810nM-—IKZF1-JurkatWO2026080794A1PGDB_A000054PGDB_C030912PGDB_AS000302View
2D structure for PGDB_C030904
DC50-=506nM-—IKZF1-JurkatWO2026080794A1PGDB_A000065PGDB_C030904PGDB_AS000302View
2D structure for PGDB_C030950
DC50-=62nM-—IKZF1-JurkatWO2026080794A1PGDB_A000132PGDB_C030950PGDB_AS000302View
2D structure for PGDB_C030832
DC50-=911nM-—IKZF1-JurkatWO2026080794A1PGDB_A000139PGDB_C030832PGDB_AS000302View
2D structure for PGDB_C030806
DC50-=1009nM-—IKZF1-JurkatWO2026080794A1PGDB_A000159PGDB_C030806PGDB_AS000302View
2D structure for PGDB_C031113
DC50-=2504nM-—IKZF1-JurkatWO2026080794A1PGDB_A000175PGDB_C031113PGDB_AS000302View
2D structure for PGDB_C030804
DC50-=1799nM-—IKZF1-JurkatWO2026080794A1PGDB_A000183PGDB_C030804PGDB_AS000302View
2D structure for PGDB_C030962
DC50-=313nM-—IKZF1-JurkatWO2026080794A1PGDB_A000259PGDB_C030962PGDB_AS000302View
2D structure for PGDB_C030911
DC50-=1238nM-—IKZF1-JurkatWO2026080794A1PGDB_A000265PGDB_C030911PGDB_AS000302View
2D structure for PGDB_C031125
DC50-=2481nM-—IKZF1-JurkatWO2026080794A1PGDB_A000303PGDB_C031125PGDB_AS000302View
2D structure for PGDB_C031002
DC50-=711nM-—IKZF1-JurkatWO2026080794A1PGDB_A000312PGDB_C031002PGDB_AS000302View
2D structure for PGDB_C030973
DC50->10000nM-—IKZF1-JurkatWO2026080794A1PGDB_A000325PGDB_C030973PGDB_AS000302View
2D structure for PGDB_C030975
DC50->10000nM-—IKZF1-JurkatWO2026080794A1PGDB_A000375PGDB_C030975PGDB_AS000302View
2D structure for PGDB_C030795
DC50->10000nM-—IKZF1-JurkatWO2026080794A1PGDB_A000400PGDB_C030795PGDB_AS000302View
2D structure for PGDB_C030898
DC50->10000nM-—IKZF1-JurkatWO2026080794A1PGDB_A000403PGDB_C030898PGDB_AS000302View
2D structure for PGDB_C030966
DC50-=23nM-—IKZF1-JurkatWO2026080794A1PGDB_A000450PGDB_C030966PGDB_AS000302View
2D structure for PGDB_C031096
DC50-=302nM-—IKZF1-JurkatWO2026080794A1PGDB_A000472PGDB_C031096PGDB_AS000302View
2D structure for PGDB_C030775
DC50->10000nM-—IKZF1-JurkatWO2026080794A1PGDB_A000478PGDB_C030775PGDB_AS000302View
2D structure for PGDB_C031100
DC50->10000nM-—IKZF1-JurkatWO2026080794A1PGDB_A000484PGDB_C031100PGDB_AS000302View
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