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COC1CCN(Cc2cc(N)nc(-c3ccc(-c4cn(C5CCC(=O)NC5=O)c(=O)o4)c(F)c3)c2)CC1| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DC50 | - | = | 62 | nM | - | — | IKZF1 | - | Jurkat | WO2026080794A1 | PGDB_A000132 | PGDB_C030950 | PGDB_AS000302 | View | |
| Dmax | - | = | 66 | % | - | 24 h | IKZF3 | - | Jurkat | WO2026080794A1 | PGDB_A004225 | PGDB_C030950 | PGDB_AS000982 | View | |
| Dmax | - | = | 83 | % | - | 24 h | IKZF1 | - | Jurkat | WO2026080794A1 | PGDB_A078399 | PGDB_C030950 | PGDB_AS000804 | View | |
| Dmax | - | = | 95 | % | - | 24 h | IKZF2 | - | Jurkat | WO2026080794A1 | PGDB_A080484 | PGDB_C030950 | PGDB_AS000354 | View | |
| DC50 | - | = | 204 | nM | - | — | IKZF3 | - | Jurkat | WO2026080794A1 | PGDB_A080508 | PGDB_C030950 | PGDB_AS000910 | View | |
| DC50 | - | = | 3 | nM | - | — | IKZF2 | - | Jurkat | WO2026080794A1 | PGDB_A081313 | PGDB_C030950 | PGDB_AS001885 | View |