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Cc1cc(-c2ccc(-c3cn(C4CCC(=O)NC4=O)c(=O)o3)c(F)c2)nc(N)c1CN1CC(C)(C)C1| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DC50 | - | = | 506 | nM | - | — | IKZF1 | - | Jurkat | WO2026080794A1 | PGDB_A000065 | PGDB_C030904 | PGDB_AS000302 | View | |
| Dmax | - | = | 72 | % | - | 24 h | IKZF1 | - | Jurkat | WO2026080794A1 | PGDB_A000989 | PGDB_C030904 | PGDB_AS000804 | View | |
| Dmax | - | = | 58 | % | - | 24 h | IKZF3 | - | Jurkat | WO2026080794A1 | PGDB_A001224 | PGDB_C030904 | PGDB_AS000982 | View | |
| DC50 | - | = | 14 | nM | - | — | IKZF2 | - | Jurkat | WO2026080794A1 | PGDB_A001375 | PGDB_C030904 | PGDB_AS001885 | View | |
| DC50 | - | = | 2495 | nM | - | — | IKZF3 | - | Jurkat | WO2026080794A1 | PGDB_A001662 | PGDB_C030904 | PGDB_AS000910 | View | |
| Dmax | - | = | 92 | % | - | 24 h | IKZF2 | - | Jurkat | WO2026080794A1 | PGDB_A080616 | PGDB_C030904 | PGDB_AS000354 | View |