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Compound
PGDB_C016637
7 activity records1 related patents
2D structure
N#Cc1ccc(Cc2ccc3c4c(cccc24)N(C2CCC(=O)NC2=O)C3=O)cc1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Emax | - | >= | 45 | % | - | DC50 > 10000 nM | DC50 >= 100 nM and <= 1000 nM | > 100 nM | - | - | KELLY.2 | WO2022081927A1 | PGDB_A013600 | PGDB_C016637 | PGDB_AS000499 | View |
| DC50 | - | > | 10000 | nM | - | — | - | - | 293T.114 | WO2022081927A1 | PGDB_A019898 | PGDB_C016637 | PGDB_AS001662 | View |
| DC50 | - | > | 10000 | nM | - | — | - | - | NCI-H929.11 | WO2022081927A1 | PGDB_A037716 | PGDB_C016637 | PGDB_AS000877 | View |
| Emax | - | > | 60 | % | - | DC50 > 10000 nM | DC50 >= 100 nM and <= 1000 nM | DC50 < 100 nM | - | - | NCI-H929.11 | WO2022081927A1 | PGDB_A065275 | PGDB_C016637 | PGDB_AS001790 | View |
| DC50 | - | > | 10000 | nM | - | — | - | - | 293T.114 | WO2022081927A1 | PGDB_A067108 | PGDB_C016637 | PGDB_AS001201 | View |
| Emax | - | > | 60 | % | - | DC50 > 10000 nM | - | - | 293T.114 | WO2022081927A1 | PGDB_A072255 | PGDB_C016637 | PGDB_AS000364 | View |
| Emax | - | > | 60 | % | - | DC50 > 10000 nM | Emax < 45% | - | - | 293T.114 | WO2022081927A1 | PGDB_A077081 | PGDB_C016637 | PGDB_AS001060 | View |