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Compound
PGDB_C016644
8 activity records1 related patents
2D structure
O=C1CCC(N2C(=O)c3ccc(CNCc4cc(F)ccc4F)c4cccc2c34)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DC50 | - | > | 10000 | nM | - | — | - | - | 293T.114 | WO2022081927A1 | PGDB_A015087 | PGDB_C016644 | PGDB_AS001662 | View |
| Emax | - | > | 60 | % | - | DC50 > 10000 nM | Emax < 45% | - | - | 293T.114 | WO2022081927A1 | PGDB_A021676 | PGDB_C016644 | PGDB_AS001060 | View |
| Emax | - | >= | 45 | % | - | DC50 > 10000 nM | DC50 >= 100 nM and <= 1000 nM | DC50 < 100 nM | - | - | NCI-H929.11 | WO2022081927A1 | PGDB_A031816 | PGDB_C016644 | PGDB_AS001790 | View |
| DC50 | - | < | 100 | nM | - | — | - | - | KELLY.2 | WO2022081927A1 | PGDB_A032313 | PGDB_C016644 | PGDB_AS001296 | View |
| Emax | - | < | 45 | % | - | DC50 > 10000 nM | DC50 >= 100 nM and <= 1000 nM | > 100 nM | - | - | KELLY.2 | WO2022081927A1 | PGDB_A047624 | PGDB_C016644 | PGDB_AS000499 | View |
| DC50 | - | > | 10000 | nM | - | — | - | - | 293T.114 | WO2022081927A1 | PGDB_A053263 | PGDB_C016644 | PGDB_AS001201 | View |
| DC50 | - | > | 10000 | nM | - | — | - | - | NCI-H929.11 | WO2022081927A1 | PGDB_A067984 | PGDB_C016644 | PGDB_AS000877 | View |
| Emax | - | > | 60 | % | - | DC50 > 10000 nM | - | - | 293T.114 | WO2022081927A1 | PGDB_A075665 | PGDB_C016644 | PGDB_AS000364 | View |