PatGlueDB | Molecular Glue Patent Bioactivity Database

Assay context summary

Assay context

69 activity records

Assay family% Degradation

Systemcell_based

Readout% Degradation

TargetIKZF2

E3CRBN

Cell lineHEK293T

Technologyfluorescence

Activity compounds and values

Activity records

69 records

Metric	Control	Relation	Value	Unit	Concentration	Time	Target	E3	Cell line	Patent	Record ID	Compound	Assay	Details
% Degradation	-	=	48.8	%	1 uM	24 h	IKZF2	CRBN	HEK293T	AR126418A1	PGDB_A008160	PGDB_C000430	PGDB_AS000416	View
% Degradation	-	<	15	%	1 uM	24 h	IKZF2	CRBN	HEK293T	AR126418A1	PGDB_A010123	PGDB_C000403	PGDB_AS000416	View
% Degradation	-	=	42.5	%	1 uM	24 h	IKZF2	CRBN	HEK293T	AR126418A1	PGDB_A012335	PGDB_C000416	PGDB_AS000416	View
% Degradation	-	=	86.7	%	1 uM	24 h	IKZF2	CRBN	HEK293T	AR126418A1	PGDB_A014928	PGDB_C000399	PGDB_AS000416	View
% Degradation	-	=	84.9	%	1 uM	24 h	IKZF2	CRBN	HEK293T	AR126418A1	PGDB_A016862	PGDB_C000409	PGDB_AS000416	View
% Degradation	-	<	15	%	1 uM	24 h	IKZF2	CRBN	HEK293T	AR126418A1	PGDB_A019354	PGDB_C000394	PGDB_AS000416	View
% Degradation	-	<	15	%	1 uM	24 h	IKZF2	CRBN	HEK293T	AR126418A1	PGDB_A020928	PGDB_C000405	PGDB_AS000416	View
% Degradation	-	=	83.8	%	1 uM	24 h	IKZF2	CRBN	HEK293T	AR126418A1	PGDB_A021431	PGDB_C000468	PGDB_AS000416	View
% Degradation	-	=	63.8	%	1 uM	24 h	IKZF2	CRBN	HEK293T	AR126418A1	PGDB_A021661	PGDB_C000460	PGDB_AS000416	View
% Degradation	-	<	15	%	1 uM	24 h	IKZF2	CRBN	HEK293T	AR126418A1	PGDB_A022499	PGDB_C000443	PGDB_AS000416	View
% Degradation	-	=	75.9	%	1 uM	24 h	IKZF2	CRBN	HEK293T	AR126418A1	PGDB_A022633	PGDB_C000462	PGDB_AS000416	View
% Degradation	-	=	63.6	%	1 uM	24 h	IKZF2	CRBN	HEK293T	AR126418A1	PGDB_A023307	PGDB_C000421	PGDB_AS000416	View
% Degradation	-	=	36.3	%	1 uM	24 h	IKZF2	CRBN	HEK293T	AR126418A1	PGDB_A024110	PGDB_C000410	PGDB_AS000416	View
% Degradation	-	=	92.3	%	1 uM	24 h	IKZF2	CRBN	HEK293T	AR126418A1	PGDB_A024583	PGDB_C000469	PGDB_AS000416	View
% Degradation	-	=	73.7	%	1 uM	24 h	IKZF2	CRBN	HEK293T	AR126418A1	PGDB_A024609	PGDB_C000423	PGDB_AS000416	View
% Degradation	-	=	87.5	%	1 uM	24 h	IKZF2	CRBN	HEK293T	AR126418A1	PGDB_A026244	PGDB_C000411	PGDB_AS000416	View
% Degradation	-	<	15	%	1 uM	24 h	IKZF2	CRBN	HEK293T	AR126418A1	PGDB_A027610	PGDB_C000444	PGDB_AS000416	View
% Degradation	-	=	85.8	%	1 uM	24 h	IKZF2	CRBN	HEK293T	AR126418A1	PGDB_A028138	PGDB_C000406	PGDB_AS000416	View
% Degradation	-	<	15	%	1 uM	24 h	IKZF2	CRBN	HEK293T	AR126418A1	PGDB_A028329	PGDB_C000417	PGDB_AS000416	View
% Degradation	-	=	77.2	%	1 uM	24 h	IKZF2	CRBN	HEK293T	AR126418A1	PGDB_A029221	PGDB_C000470	PGDB_AS000416	View

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