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Compound
PGDB_C000430
6 activity records3 related patents
2D structure
N#Cc1cc(Cl)ccc1C1CN([C@H]2CCC[C@@H]2Oc2ccc3c(c2)CN(C2CCC(=O)NC2=O)C3=O)C1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | = | 48.8 | % | 1 uM | 24 h | IKZF2 | CRBN | HEK293T | AR126418A1 | PGDB_A008160 | PGDB_C000430 | PGDB_AS000416 | View |
| % Degradation | - | = | 48.8 | % | 1 uM | 24 h | IKZF2 | CRBN | HEK293T | CN117836288A | PGDB_A052845 | PGDB_C000430 | PGDB_AS002458 | View |
| % Degradation | - | = | 48.8 | % | 1 uM | 24 h | IKZF2 | - | HEK293T | US20230265071A1 | PGDB_A060343 | PGDB_C000430 | PGDB_AS000278 | View |
| EC50 | - | = | 0.036 | uM | - | — | IKZF2 | CRBN | HEK293T | AR126418A1 | PGDB_A066084 | PGDB_C000430 | PGDB_AS001328 | View |
| EC50 | - | = | 0.036 | uM | - | — | CRBN | CRBN | HEK293T | CN117836288A | PGDB_A069455 | PGDB_C000430 | PGDB_AS001696 | View |
| EC50 | - | = | 0.036 | uM | - | — | CRBN | CRBN | - | US20230265071A1 | PGDB_A074721 | PGDB_C000430 | PGDB_AS001482 | View |