Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C000421
6 activity records3 related patents
2D structure
O=C1CCC(N2Cc3cc(O[C@H]4CCC[C@@H]4N4CC(c5ccc(-n6cccn6)cc5)C4)ccc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | = | 63.6 | % | 1 uM | 24 h | IKZF2 | CRBN | HEK293T | CN117836288A | PGDB_A015365 | PGDB_C000421 | PGDB_AS002458 | View |
| % Degradation | - | = | 63.6 | % | 1 uM | 24 h | IKZF2 | CRBN | HEK293T | AR126418A1 | PGDB_A023307 | PGDB_C000421 | PGDB_AS000416 | View |
| EC50 | - | = | 0.005 | uM | - | — | IKZF2 | CRBN | HEK293T | AR126418A1 | PGDB_A047453 | PGDB_C000421 | PGDB_AS001328 | View |
| EC50 | - | = | 0.005 | uM | - | — | CRBN | CRBN | HEK293T | CN117836288A | PGDB_A048319 | PGDB_C000421 | PGDB_AS001696 | View |
| % Degradation | - | = | 63.6 | % | 1 uM | 24 h | IKZF2 | - | HEK293T | US20230265071A1 | PGDB_A051529 | PGDB_C000421 | PGDB_AS000278 | View |
| EC50 | - | = | 0.005 | uM | - | — | CRBN | CRBN | - | US20230265071A1 | PGDB_A065133 | PGDB_C000421 | PGDB_AS001482 | View |