Assay

PGDB_AS000438

System: biochemicalTarget: CRBN
Assay context summary

Assay context

12 activity records
Assay familybinding
Systembiochemical
ReadoutIC50
TargetCRBN
E3CRBN
Technologyfluorescence
Activity compounds and values

Activity records

12 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C011110
IC50->1100nM-—CRBNCRBN-WO2022219412A1PGDB_A009813PGDB_C011110PGDB_AS000438View
2D structure for PGDB_C001724
IC50-<=500nM-—CRBNCRBN-WO2022219412A1PGDB_A015055PGDB_C001724PGDB_AS000438View
2D structure for PGDB_C001740
IC50->1700nM-—CRBNCRBN-WO2022219412A1PGDB_A023915PGDB_C001740PGDB_AS000438View
2D structure for PGDB_C025999
IC50->500nM-—CRBNCRBN-WO2022219412A1PGDB_A025438PGDB_C025999PGDB_AS000438View
2D structure for PGDB_C001726
IC50->1700nM-—CRBNCRBN-WO2022219412A1PGDB_A027535PGDB_C001726PGDB_AS000438View
2D structure for PGDB_C026003
IC50->1700nM-—CRBNCRBN-WO2022219412A1PGDB_A030140PGDB_C026003PGDB_AS000438View
2D structure for PGDB_C001738
IC50->1100nM-—CRBNCRBN-WO2022219412A1PGDB_A033813PGDB_C001738PGDB_AS000438View
2D structure for PGDB_C001728
IC50->500nM-—CRBNCRBN-WO2022219412A1PGDB_A036737PGDB_C001728PGDB_AS000438View
2D structure for PGDB_C001746
IC50->1100nM-—CRBNCRBN-WO2022219412A1PGDB_A049505PGDB_C001746PGDB_AS000438View
2D structure for PGDB_C001744
IC50->500nM-—CRBNCRBN-WO2022219412A1PGDB_A051377PGDB_C001744PGDB_AS000438View
2D structure for PGDB_C001736
IC50->1700nM-—CRBNCRBN-WO2022219412A1PGDB_A064502PGDB_C001736PGDB_AS000438View
2D structure for PGDB_C001742
IC50->500nM-—CRBNCRBN-WO2022219412A1PGDB_A070261PGDB_C001742PGDB_AS000438View
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