PatGlueDB | Molecular Glue Patent Bioactivity Database

Assay context summary

Assay context

37 activity records

Assay familyviability

Systemcell_based

ReadoutIC50

E3Not specified

Cell lineCCRF-CEM

OrganismHomo sapiens

Detection target% Cell viability

Activity compounds and values

Activity records

37 records

Metric	Control	Relation	Value	Unit	Concentration	Time	Target	E3	Cell line	Patent	Record ID	Compound	Assay	Details
IC50	-	=	1-5	nM	-	—	IKZF3	-	CCRF-CEM	WO2025016359A1	PGDB_A010159	PGDB_C019195	PGDB_AS000461	View
IC50	-	=	1-5	nM	-	—	IKZF3	-	CCRF-CEM	WO2025016359A1	PGDB_A011516	PGDB_C019199	PGDB_AS000461	View
IC50	-	=	1-5	nM	-	—	IKZF3	-	CCRF-CEM	WO2025016359A1	PGDB_A016498	PGDB_C019176	PGDB_AS000461	View
IC50	-	=	10-50	nM	-	—	IKZF3	-	CCRF-CEM	WO2025016359A1	PGDB_A023860	PGDB_C019178	PGDB_AS000461	View
IC50	-	=	10-50	nM	-	—	IKZF3	-	CCRF-CEM	WO2025016359A1	PGDB_A024172	PGDB_C019179	PGDB_AS000461	View
IC50	-	=	5-10	nM	-	—	IKZF3	-	CCRF-CEM	WO2025016359A1	PGDB_A026156	PGDB_C019201	PGDB_AS000461	View
IC50	-	=	100-500	nM	-	—	IKZF3	-	CCRF-CEM	WO2025016359A1	PGDB_A029586	PGDB_C019187	PGDB_AS000461	View
IC50	-	=	10-50	nM	-	—	IKZF3	-	CCRF-CEM	WO2025016359A1	PGDB_A030396	PGDB_C019228	PGDB_AS000461	View
IC50	-	=	10-50	nM	-	—	IKZF3	-	CCRF-CEM	WO2025016359A1	PGDB_A031732	PGDB_C019222	PGDB_AS000461	View
IC50	-	=	1-5	nM	-	—	IKZF3	-	CCRF-CEM	WO2025016359A1	PGDB_A033192	PGDB_C019221	PGDB_AS000461	View
IC50	-	=	5-10	nM	-	—	IKZF3	-	CCRF-CEM	WO2025016359A1	PGDB_A033598	PGDB_C019202	PGDB_AS000461	View
IC50	-	=	10-50	nM	-	—	IKZF3	-	CCRF-CEM	WO2025016359A1	PGDB_A037544	PGDB_C019186	PGDB_AS000461	View
IC50	-	=	5-10	nM	-	—	IKZF3	-	CCRF-CEM	WO2025016359A1	PGDB_A037791	PGDB_C019196	PGDB_AS000461	View
IC50	-	=	1-5	nM	-	—	IKZF3	-	CCRF-CEM	WO2025016359A1	PGDB_A039532	PGDB_C019218	PGDB_AS000461	View
IC50	-	=	10-50	nM	-	—	IKZF3	-	CCRF-CEM	WO2025016359A1	PGDB_A045029	PGDB_C019197	PGDB_AS000461	View
IC50	-	<	1	nM	-	—	IKZF3	-	CCRF-CEM	WO2025016359A1	PGDB_A047976	PGDB_C019227	PGDB_AS000461	View
IC50	-	=	10-50	nM	-	—	IKZF3	-	CCRF-CEM	WO2025016359A1	PGDB_A048228	PGDB_C019185	PGDB_AS000461	View
IC50	-	=	5-10	nM	-	—	IKZF3	-	CCRF-CEM	WO2025016359A1	PGDB_A048802	PGDB_C019182	PGDB_AS000461	View
IC50	-	=	50-100	nM	-	—	IKZF3	-	CCRF-CEM	WO2025016359A1	PGDB_A049810	PGDB_C019214	PGDB_AS000461	View
IC50	-	=	10-50	nM	-	—	IKZF3	-	CCRF-CEM	WO2025016359A1	PGDB_A050187	PGDB_C019203	PGDB_AS000461	View

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