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Compound
PGDB_C011613
10 activity records1 related patents
2D structure
CCn1c(-c2cc(C#CCN3CCO[C@H](C(=O)N(C)C)C3)cnc2[C@H](C)OC)c2c3cc(ccc31)-c1csc(n1)C[C@H](NC(=O)[C@H]1[C@H](C)[C@@H]1C)C(=O)N1N[C@@H](CC1C)C(=O)OCC(C)(C)C2Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | <= | 1 | nM | - | — | KRAS | - | SW620 | WO2025214350A1 | PGDB_A012246 | PGDB_C011613 | PGDB_AS001156 | View |
| IC50 | - | <= | 1 | nM | - | — | KRAS | - | AGS | WO2025214350A1 | PGDB_A025827 | PGDB_C011613 | PGDB_AS000218 | View |
| IC50 | - | = | 1-10 | nM | - | — | KRAS | - | - | WO2025214350A1 | PGDB_A031551 | PGDB_C011613 | PGDB_AS002054 | View |
| IC50 | - | = | 1-10 | nM | - | — | KRAS | - | - | WO2025214350A1 | PGDB_A034347 | PGDB_C011613 | PGDB_AS000791 | View |
| IC50 | - | = | 1-10 | nM | - | — | KRAS | - | - | WO2025214350A1 | PGDB_A038637 | PGDB_C011613 | PGDB_AS000307 | View |
| IC50 | - | = | 1-10 | nM | - | — | KRAS | - | - | WO2025214350A1 | PGDB_A041020 | PGDB_C011613 | PGDB_AS001818 | View |
| IC50 | - | <= | 1 | nM | - | — | - | - | AsPC-1 | WO2025214350A1 | PGDB_A042269 | PGDB_C011613 | PGDB_AS001410 | View |
| IC50 | - | <= | 1 | nM | - | — | KRAS | - | NCI-H358 | WO2025214350A1 | PGDB_A049199 | PGDB_C011613 | PGDB_AS001442 | View |
| IC50 | - | = | 1-10 | nM | - | — | KRAS | - | - | WO2025214350A1 | PGDB_A057069 | PGDB_C011613 | PGDB_AS000928 | View |
| IC50 | - | <= | 1 | nM | - | — | KRAS | - | HPAC | WO2025214350A1 | PGDB_A071304 | PGDB_C011613 | PGDB_AS002124 | View |