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Compound
PGDB_C011588
10 activity records1 related patents
2D structure
C#Cc1cnc([C@H](C)OC)c(-c2c3c4cc(ccc4n2CC)-c2csc(n2)C[C@H](NC(=O)[C@H]2C[C@@H]2C)C(=O)N2N[C@H](C(=O)OCC(C)(C)C3)C3CC2C3)c1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 10-100 | nM | - | — | KRAS | - | - | WO2025214350A1 | PGDB_A010747 | PGDB_C011588 | PGDB_AS001818 | View |
| IC50 | - | = | 10-100 | nM | - | — | KRAS | - | - | WO2025214350A1 | PGDB_A015997 | PGDB_C011588 | PGDB_AS002054 | View |
| IC50 | - | = | 100-1000 | nM | - | — | KRAS | - | - | WO2025214350A1 | PGDB_A022801 | PGDB_C011588 | PGDB_AS000307 | View |
| IC50 | - | = | 10-100 | nM | - | — | KRAS | - | - | WO2025214350A1 | PGDB_A026494 | PGDB_C011588 | PGDB_AS000791 | View |
| IC50 | - | = | 1-10 | nM | - | — | KRAS | - | NCI-H358 | WO2025214350A1 | PGDB_A031762 | PGDB_C011588 | PGDB_AS001442 | View |
| IC50 | - | = | 10-100 | nM | - | — | KRAS | - | HPAC | WO2025214350A1 | PGDB_A041856 | PGDB_C011588 | PGDB_AS002124 | View |
| IC50 | - | = | 10-100 | nM | - | — | - | - | AsPC-1 | WO2025214350A1 | PGDB_A047986 | PGDB_C011588 | PGDB_AS001410 | View |
| IC50 | - | = | 10-100 | nM | - | — | KRAS | - | AGS | WO2025214350A1 | PGDB_A051409 | PGDB_C011588 | PGDB_AS000218 | View |
| IC50 | - | = | 10-100 | nM | - | — | KRAS | - | SW620 | WO2025214350A1 | PGDB_A062070 | PGDB_C011588 | PGDB_AS001156 | View |
| IC50 | - | = | 100-1000 | nM | - | — | KRAS | - | - | WO2025214350A1 | PGDB_A070522 | PGDB_C011588 | PGDB_AS000928 | View |