Assay
PGDB_AS001060
System: cell_basedTarget: GSPT1Cell line: 293T.114
Assay context summary
Assay context
Activity compounds and values
Activity records
| Structure | Metric | Control | Relation | Value | Unit | Concentration | Time | Target | E3 | Cell line | Patent | Record ID | Compound | Assay | Details |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 | Emax | - | > | 60 | % | - | DC50 > 10000 nM | Emax < 45% | - | - | 293T.114 | WO2022081927A1 | PGDB_A021676 | PGDB_C016644 | PGDB_AS001060 | View |
 | Emax | - | < | 45 | % | - | DC50 > 10000 nM | Emax < 45% | - | - | 293T.114 | WO2022081927A1 | PGDB_A026617 | PGDB_C026764 | PGDB_AS001060 | View |
 | Emax | - | > | 60 | % | - | DC50 > 10000 nM | Emax < 45% | - | - | 293T.114 | WO2022081927A1 | PGDB_A039079 | PGDB_C016648 | PGDB_AS001060 | View |
 | Emax | - | > | 60 | % | - | DC50 > 10000 nM | Emax < 45% | - | - | 293T.114 | WO2022081927A1 | PGDB_A073878 | PGDB_C016646 | PGDB_AS001060 | View |
 | Emax | - | > | 60 | % | - | DC50 > 10000 nM | Emax < 45% | - | - | 293T.114 | WO2022081927A1 | PGDB_A077081 | PGDB_C016637 | PGDB_AS001060 | View |