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Compound
PGDB_C005828
2 activity records1 related patents
2D structure
CO[C@@H]1CCN(S(=O)(=O)Nc2ccc(F)c(Oc3ccc4ncn([C@H]5COC6(CCN(C(=O)CC7(O)CCN(c8cc9c(cc8F)N8C(=O)NC(=O)CCC8=NN9C)CC7)CC6)C5)c(=O)c4c3)c2C#N)C1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DC50 | - | = | 18.04 | nM | - | — | BRAF | - | A375.10 | AU2022290851A1 | PGDB_A020509 | PGDB_C005828 | PGDB_AS001308 | View |
| Emax | - | = | 22.3 | % | 10 uM | 24 h | BRAF | - | A375.10 | AU2022290851A1 | PGDB_A040799 | PGDB_C005828 | PGDB_AS000362 | View |