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Compound
PGDB_C011621
10 activity records1 related patents
2D structure
CCn1c(-c2cc(C#CCN3CCOCC3)cnc2[C@H](C)OC)c2c3cc(ccc31)N1CCO[C@@H](C[C@H](NC(=O)[C@H]3[C@H](C)[C@@H]3C)C(=O)N3N[C@@H](CC3C)C(=O)OCC(C)(C)C2)C1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 100-1000 | nM | - | — | KRAS | - | NCI-H358 | WO2025214350A1 | PGDB_A009873 | PGDB_C011621 | PGDB_AS001442 | View |
| IC50 | - | > | 1000 | nM | - | — | KRAS | - | HPAC | WO2025214350A1 | PGDB_A015330 | PGDB_C011621 | PGDB_AS002124 | View |
| IC50 | - | > | 1000 | nM | - | — | - | - | AsPC-1 | WO2025214350A1 | PGDB_A015477 | PGDB_C011621 | PGDB_AS001410 | View |
| IC50 | - | = | 100-1000 | nM | - | — | KRAS | - | - | WO2025214350A1 | PGDB_A018838 | PGDB_C011621 | PGDB_AS000928 | View |
| IC50 | - | = | 10-100 | nM | - | — | KRAS | - | - | WO2025214350A1 | PGDB_A032865 | PGDB_C011621 | PGDB_AS000307 | View |
| IC50 | - | = | 100-1000 | nM | - | — | KRAS | - | - | WO2025214350A1 | PGDB_A041516 | PGDB_C011621 | PGDB_AS000791 | View |
| IC50 | - | = | 100-1000 | nM | - | — | KRAS | - | - | WO2025214350A1 | PGDB_A045276 | PGDB_C011621 | PGDB_AS002054 | View |
| IC50 | - | > | 1000 | nM | - | — | KRAS | - | AGS | WO2025214350A1 | PGDB_A054773 | PGDB_C011621 | PGDB_AS000218 | View |
| IC50 | - | = | 10-100 | nM | - | — | KRAS | - | SW620 | WO2025214350A1 | PGDB_A077242 | PGDB_C011621 | PGDB_AS001156 | View |
| IC50 | - | = | 10-100 | nM | - | — | KRAS | - | - | WO2025214350A1 | PGDB_A077452 | PGDB_C011621 | PGDB_AS001818 | View |