Summary
AssigneeSanofi Aventis France
Filing years2023
Patents1
Compounds41
Activity records90
Patent families1
Targets2
Assay familiesdegradation
Activity metricsIC50, degradation
Overview

Target distribution and active-compound trend

Target distribution

90 activity records

2 targets

Active compounds by publication year

Distinct compounds linked to assignee patent publications

021412024
Activity compounds and values

Activity records

90 records
Structure
Control
Value
ConcentrationTime
Record IDCompoundAssayDetails
2D structure for PGDB_C006912
IC50-=0.8nM-ESR1-MCF-7CN118984820APGDB_A008714PGDB_C006912PGDB_AS000996View
2D structure for PGDB_C006920
IC50-=1.3nM-ESR1-MCF-7CN118984820APGDB_A012432PGDB_C006920PGDB_AS000996View
2D structure for PGDB_C006901
IC50-=0.8nM-ESR1-MCF-7CN118984820APGDB_A012912PGDB_C006901PGDB_AS000996View
2D structure for PGDB_C006923
IC50-=0.4nM-ER-LNCaPCN118984820APGDB_A013406PGDB_C006923PGDB_AS001923View
2D structure for PGDB_C006920
IC50-=78.8nM-ESR1-MCF-7CN118984820APGDB_A013992PGDB_C006920PGDB_AS000996View
2D structure for PGDB_C006914
IC50-=0.8nM-ESR1-MCF-7CN118984820APGDB_A014181PGDB_C006914PGDB_AS000996View
2D structure for PGDB_C006889
IC50-=5.4nM-ESR1-MCF-7CN118984820APGDB_A014290PGDB_C006889PGDB_AS000996View
2D structure for PGDB_C006913
IC50-=0.9nM-ESR1-MCF-7CN118984820APGDB_A015732PGDB_C006913PGDB_AS000996View
2D structure for PGDB_C006886
IC50-=1.5nM-ESR1-MCF-7CN118984820APGDB_A016145PGDB_C006886PGDB_AS000996View
2D structure for PGDB_C006894
% Degradation-=90%--ESR1-MCF-7CN118984820APGDB_A016717PGDB_C006894PGDB_AS001441View
2D structure for PGDB_C006922
IC50-=1.2nM-ESR1-MCF-7CN118984820APGDB_A017455PGDB_C006922PGDB_AS000996View
2D structure for PGDB_C006919
IC50-=1.6nM-ESR1-MCF-7CN118984820APGDB_A017584PGDB_C006919PGDB_AS000996View
2D structure for PGDB_C006887
% Degradation-=80%--ESR1-MCF-7CN118984820APGDB_A019029PGDB_C006887PGDB_AS001441View
2D structure for PGDB_C006903
% Degradation-=69%--ESR1-MCF-7CN118984820APGDB_A019710PGDB_C006903PGDB_AS001441View
2D structure for PGDB_C006918
IC50-=2nM-ESR1-MCF-7CN118984820APGDB_A019931PGDB_C006918PGDB_AS000996View
2D structure for PGDB_C006891
IC50-=1.4nM-ESR1-MCF-7CN118984820APGDB_A021332PGDB_C006891PGDB_AS000996View
2D structure for PGDB_C006906
IC50-=0.9nM-ESR1-MCF-7CN118984820APGDB_A021898PGDB_C006906PGDB_AS000996View
2D structure for PGDB_C006906
% Degradation-=73%--ESR1-MCF-7CN118984820APGDB_A022724PGDB_C006906PGDB_AS001441View
2D structure for PGDB_C006892
IC50-=0.3nM-ESR1-MCF-7CN118984820APGDB_A023258PGDB_C006892PGDB_AS000996View
2D structure for PGDB_C006905
% Degradation-=84%--ESR1-MCF-7CN118984820APGDB_A024639PGDB_C006905PGDB_AS001441View