Summary
AssigneeYangtze River Pharmaceutical Group
Filing years2025
Patents1
Compounds37
Activity records24
Patent families1
Targets3
Assay familiesdegradation
Activity metricsDC50
Overview

Target distribution and active-compound trend

Target distribution

75 activity records

4 targets

Active compounds by publication year

Distinct compounds linked to assignee patent publications

019372026
Activity compounds and values

Activity records

75 records
Structure
Control
Value
ConcentrationTime
Record IDCompoundAssayDetails
2D structure for PGDB_C003368
IC50-=8nM---MDA-MB-453WO2026007898A1PGDB_A009179PGDB_C003368PGDB_AS002028View
2D structure for PGDB_C003376
IC50-=1.2nM---MDA-MB-453WO2026007898A1PGDB_A009278PGDB_C003376PGDB_AS002028View
2D structure for PGDB_C003375
IC50-=1834nM---MDA-MB-453WO2026007898A1PGDB_A010585PGDB_C003375PGDB_AS002028View
2D structure for PGDB_C003382
DC50-=1648nM-IKZF1--WO2026007898A1PGDB_A010967PGDB_C003382PGDB_AS002166View
2D structure for PGDB_C003396
DC50-=77nM-GSPT1--WO2026007898A1PGDB_A010972PGDB_C003396PGDB_AS002374View
2D structure for PGDB_C003397
DC50->10000nM-IKZF3--WO2026007898A1PGDB_A011249PGDB_C003397PGDB_AS002393View
2D structure for PGDB_C003385
IC50-=2nM---MDA-MB-453WO2026007898A1PGDB_A011614PGDB_C003385PGDB_AS002028View
2D structure for PGDB_C003388
IC50-=267nM---MDA-MB-453WO2026007898A1PGDB_A013277PGDB_C003388PGDB_AS002028View
2D structure for PGDB_C003400
Selectivity index->270fold----WO2026007898A1PGDB_A014241PGDB_C003400PGDB_AS001314View
2D structure for PGDB_C003372
IC50-=51nM---MDA-MB-453WO2026007898A1PGDB_A014408PGDB_C003372PGDB_AS002028View
2D structure for PGDB_C003367
IC50-=2nM---MDA-MB-453WO2026007898A1PGDB_A014982PGDB_C003367PGDB_AS002028View
2D structure for PGDB_C003382
Selectivity index-=16fold----WO2026007898A1PGDB_A017836PGDB_C003382PGDB_AS001314View
2D structure for PGDB_C003391
IC50-=39nM---MDA-MB-453WO2026007898A1PGDB_A018125PGDB_C003391PGDB_AS002028View
2D structure for PGDB_C003379
DC50->10000nM-IKZF1--WO2026007898A1PGDB_A018934PGDB_C003379PGDB_AS002166View
2D structure for PGDB_C003380
IC50-=151nM---MDA-MB-453WO2026007898A1PGDB_A021331PGDB_C003380PGDB_AS002028View
2D structure for PGDB_C003396
Selectivity index->130fold----WO2026007898A1PGDB_A022505PGDB_C003396PGDB_AS001314View
2D structure for PGDB_C003390
IC50-=109nM---MDA-MB-453WO2026007898A1PGDB_A023331PGDB_C003390PGDB_AS002028View
2D structure for PGDB_C003374
IC50-=45nM---MDA-MB-453WO2026007898A1PGDB_A023492PGDB_C003374PGDB_AS002028View
2D structure for PGDB_C003383
IC50-=3nM---MDA-MB-453WO2026007898A1PGDB_A023742PGDB_C003383PGDB_AS002028View
2D structure for PGDB_C003379
Selectivity index->2012fold----WO2026007898A1PGDB_A024503PGDB_C003379PGDB_AS001314View