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Compound
PGDB_C003382
9 activity records2 related patents
2D structure
CNCCOCCc1ccc(NC(=O)NCc2ccc3c(c2)CN(C2CCC(=O)NC2=O)C3=O)cc1ClCompound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 62.69 | nM | - | — | GSPT1 | - | SK-BR-3 | WO2025252247A1 | PGDB_A010893 | PGDB_C003382 | PGDB_AS000582 | View |
| DC50 | - | = | 1648 | nM | - | — | IKZF1 | - | - | WO2026007898A1 | PGDB_A010967 | PGDB_C003382 | PGDB_AS002166 | View |
| Selectivity index | IKZF1 | = | 16 | fold | - | — | - | - | - | WO2026007898A1 | PGDB_A017836 | PGDB_C003382 | PGDB_AS001314 | View |
| IC50 | - | = | 121.46 | nM | - | — | GSPT1 | - | SK-BR-3 | WO2025252247A1 | PGDB_A024823 | PGDB_C003382 | PGDB_AS001340 | View |
| DC50 | - | = | 5815 | nM | - | — | IKZF3 | - | - | WO2026007898A1 | PGDB_A041106 | PGDB_C003382 | PGDB_AS002393 | View |
| IC50 | - | = | 439 | nM | - | — | - | - | MDA-MB-453 | WO2026007898A1 | PGDB_A043812 | PGDB_C003382 | PGDB_AS002028 | View |
| DC50 | - | = | 34.58 | nM | - | — | GSPT1 | - | HEK293 | WO2025252247A1 | PGDB_A051267 | PGDB_C003382 | PGDB_AS000196 | View |
| Selectivity index | IKZF3 | = | 56.5 | fold | - | — | - | - | - | WO2026007898A1 | PGDB_A052899 | PGDB_C003382 | PGDB_AS000375 | View |
| DC50 | - | = | 103 | nM | - | — | GSPT1 | - | - | WO2026007898A1 | PGDB_A070865 | PGDB_C003382 | PGDB_AS002374 | View |