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Compound
PGDB_C000344
4 activity records1 related patents
2D structure
COc1nc(OC)nc(N2CC(CN3CCN(c4cccc5c4C(=O)N(C4CCC(=O)NC4=O)C5=O)CC3)C2)n1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 200-2000 | nM | - | — | - | - | Raji | CN117683022A | PGDB_A011896 | PGDB_C000344 | PGDB_AS000751 | View |
| % Degradation | - | = | 10-30 | % | 1 uM | - | BRD4 | - | - | CN117683022A | PGDB_A029149 | PGDB_C000344 | PGDB_AS002272 | View |
| IC50 | - | = | 2000-4000 | nM | - | — | - | - | THP-1 | CN117683022A | PGDB_A054354 | PGDB_C000344 | PGDB_AS000289 | View |
| % Degradation | - | = | 30-60 | % | 1 uM | - | GSPT1 | - | - | CN117683022A | PGDB_A059276 | PGDB_C000344 | PGDB_AS001783 | View |