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Compound
PGDB_C000355
5 activity records2 related patents
2D structure
O=C(C#Cc1ccccc1)NCc1ccc2c(c1)CN(C1CCC(=O)NC1=O)C2=OCompound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | = | 60-80 | % | 1 uM | - | GSPT1 | - | - | CN117683022A | PGDB_A010675 | PGDB_C000355 | PGDB_AS001783 | View |
| % Degradation | - | = | 30-60 | % | 1 uM | - | BRD4 | - | - | CN117683022A | PGDB_A032566 | PGDB_C000355 | PGDB_AS002272 | View |
| IC50 | - | < | 1 | nM | - | — | - | - | MV-4-11 | WO2023274246A1 | PGDB_A060638 | PGDB_C000355 | PGDB_AS002583 | View |
| IC50 | - | = | 66.6 | nM | - | — | - | - | THP-1 | CN117683022A | PGDB_A060958 | PGDB_C000355 | PGDB_AS000289 | View |
| IC50 | - | = | 45.5 | nM | - | — | - | - | Raji | CN117683022A | PGDB_A067816 | PGDB_C000355 | PGDB_AS000751 | View |