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Compound
PGDB_C000518
7 activity records2 related patents
2D structure
Cc1c(Cl)cc(NC(=O)CCc2ccc3c(c2)C(=O)N(C2CCC(=O)NC2=O)C3)cc1CN1CCOCC1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | = | 0 | % | Concentration series: 30 uM, 3 uM, 0.3 uM | - | IKZF1 | - | - | WO2022219412A1 | PGDB_A037233 | PGDB_C000518 | PGDB_AS002537 | View |
| % Degradation | - | < | 50 | % | 30 uM | - | CSNK1A1 | - | - | WO2022219412A1 | PGDB_A044199 | PGDB_C000518 | PGDB_AS000516 | View |
| % Degradation | - | < | 50 | % | Concentration series: 30 uM, 3 uM, 0.3 uM | - | ZFP91 | - | - | WO2022219412A1 | PGDB_A048813 | PGDB_C000518 | PGDB_AS000241 | View |
| DC50 | - | = | 48 | nM | - | — | GSPT1 | - | U937 | CN117917402A | PGDB_A059622 | PGDB_C000518 | PGDB_AS002566 | View |
| % Degradation | - | > | 90 | % | 0.3 uM | - | GSPT1 | - | - | WO2022219412A1 | PGDB_A065575 | PGDB_C000518 | PGDB_AS001648 | View |
| DC50 | - | = | 6 | nM | - | — | - | - | MM.1S | WO2022219412A1 | PGDB_A066413 | PGDB_C000518 | PGDB_AS001567 | View |
| % Degradation | - | < | 50 | % | 30 uM | - | IKZF3 | - | - | WO2022219412A1 | PGDB_A068137 | PGDB_C000518 | PGDB_AS001625 | View |