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Compound
PGDB_C000755
8 activity records1 related patents
2D structure
O=C1CCC(N2Cc3cc(CN4CCC(N5CCN(c6noc7cc(F)ccc67)CC5)C(F)(F)C4)ccc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | = | 0-20 | % | Concentration series: 500 nM, 50 nM | 24 h | CSNK1A1 | - | - | CN120548310A | PGDB_A009941 | PGDB_C000755 | PGDB_AS001449 | View |
| % Degradation | - | = | 0-20 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF2 | - | - | CN120548310A | PGDB_A027083 | PGDB_C000755 | PGDB_AS002025 | View |
| % Degradation | - | = | 0-20 | % | Concentration series: 500 nM, 50 nM | 24 h | WEE1 | - | - | CN120548310A | PGDB_A033033 | PGDB_C000755 | PGDB_AS001655 | View |
| % Degradation | - | >= | 20 | % | Concentration series: 500 nM, 50 nM | 24 h | GSPT1 | - | - | CN120548310A | PGDB_A044690 | PGDB_C000755 | PGDB_AS001466 | View |
| IC50 | - | = | 100-200 | nM | - | — | - | - | MM.1S | CN120548310A | PGDB_A055415 | PGDB_C000755 | PGDB_AS000141 | View |
| % Degradation | - | = | 0-20 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF1 | - | - | CN120548310A | PGDB_A060493 | PGDB_C000755 | PGDB_AS000946 | View |
| IC50 | - | <= | 0.1 | uM | - | — | CRBN | CRBN | - | CN120548310A | PGDB_A065577 | PGDB_C000755 | PGDB_AS000323 | View |
| % Degradation | - | >= | 20 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF3 | - | - | CN120548310A | PGDB_A066684 | PGDB_C000755 | PGDB_AS000102 | View |