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Compound
PGDB_C000759
7 activity records1 related patents
2D structure
O=C1CCC(N2Cc3cc(CN4CCC(N5CCN(C(c6ccccc6)c6ccccc6)CC5)CC4)c(F)cc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 1-1.5 | uM | - | — | CRBN | CRBN | - | CN120548310A | PGDB_A019646 | PGDB_C000759 | PGDB_AS000323 | View |
| % Degradation | - | = | 0-20 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF3 | - | - | CN120548310A | PGDB_A036736 | PGDB_C000759 | PGDB_AS000102 | View |
| % Degradation | - | >= | 20 | % | Concentration series: 500 nM, 50 nM | 24 h | GSPT1 | - | - | CN120548310A | PGDB_A037502 | PGDB_C000759 | PGDB_AS001466 | View |
| % Degradation | - | >= | 20 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF2 | - | - | CN120548310A | PGDB_A048414 | PGDB_C000759 | PGDB_AS002025 | View |
| % Degradation | - | = | 0-20 | % | Concentration series: 500 nM, 50 nM | 24 h | CSNK1A1 | - | - | CN120548310A | PGDB_A053034 | PGDB_C000759 | PGDB_AS001449 | View |
| % Degradation | - | = | 0-20 | % | Concentration series: 500 nM, 50 nM | 24 h | WEE1 | - | - | CN120548310A | PGDB_A057740 | PGDB_C000759 | PGDB_AS001655 | View |
| % Degradation | - | = | 0-20 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF1 | - | - | CN120548310A | PGDB_A064270 | PGDB_C000759 | PGDB_AS000946 | View |