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Cc1ccccc1[C@@H](NC(=O)c1ccc2c(c1)CN(C1CCC(=O)NC1=O)C2=O)C1CC1| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dmax | - | = | 32.5 | % | 10 uM | 20 h | GSPT1 | CRBN | HT-1080 | WO2022257897A1 | PGDB_A015766 | PGDB_C001805 | PGDB_AS000618 | View | |
| Dmax | - | = | 61 | % | 10 uM | 20 h | CSNK1A1 | CRBN | HT-1080 | WO2022257897A1 | PGDB_A017323 | PGDB_C001805 | PGDB_AS000920 | View | |
| DC50 | - | = | 0.363 | uM | - | — | CSNK1A1 | CRBN | HT-1080 | WO2022257897A1 | PGDB_A036789 | PGDB_C001805 | PGDB_AS001868 | View |