Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C001806
3 activity records1 related patents
2D structure
O=C1CCC(N2Cc3cc(C(=O)NC(c4ccc(F)c(F)c4)C4CCC4)ccc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dmax | - | = | 30.6 | % | 10 uM | 20 h | GSPT1 | CRBN | HT-1080 | WO2022257897A1 | PGDB_A011475 | PGDB_C001806 | PGDB_AS000618 | View |
| DC50 | - | = | 0.416 | uM | - | — | CSNK1A1 | CRBN | HT-1080 | WO2022257897A1 | PGDB_A061380 | PGDB_C001806 | PGDB_AS001868 | View |
| Dmax | - | = | 57.5 | % | 10 uM | 20 h | CSNK1A1 | CRBN | HT-1080 | WO2022257897A1 | PGDB_A073180 | PGDB_C001806 | PGDB_AS000920 | View |