Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C001815
6 activity records1 related patents
2D structure
O=C1CC[C@H](N2Cc3cc(C(=O)N[C@H](c4ccc(F)cc4Cl)C4CCC4)ccc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dmax | - | = | 70.2 | % | 10 uM | 20 h | CSNK1A1 | CRBN | HT-1080 | WO2022257897A1 | PGDB_A012948 | PGDB_C001815 | PGDB_AS000920 | View |
| Dmax | - | = | 62.3 | % | 10 uM | 20 h | CSNK1A1 | CRBN | HT-1080 | WO2022257897A1 | PGDB_A015743 | PGDB_C001815 | PGDB_AS000920 | View |
| Dmax | - | = | 24.2 | % | 10 uM | 20 h | GSPT1 | CRBN | HT-1080 | WO2022257897A1 | PGDB_A017558 | PGDB_C001815 | PGDB_AS000618 | View |
| DC50 | - | = | 0.142 | uM | - | — | CSNK1A1 | CRBN | HT-1080 | WO2022257897A1 | PGDB_A021364 | PGDB_C001815 | PGDB_AS001868 | View |
| DC50 | - | = | 0.118 | uM | - | — | CSNK1A1 | CRBN | HT-1080 | WO2022257897A1 | PGDB_A046638 | PGDB_C001815 | PGDB_AS001868 | View |
| Dmax | - | = | 46 | % | 10 uM | 20 h | GSPT1 | CRBN | HT-1080 | WO2022257897A1 | PGDB_A049966 | PGDB_C001815 | PGDB_AS000618 | View |