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Compound
PGDB_C001816
6 activity records1 related patents
2D structure
O=C1CC[C@@H](N2Cc3cc(C(=O)N[C@H](c4ccc(Cl)cc4F)C4CCC4)ccc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dmax | - | = | 47.9 | % | 10 uM | 20 h | GSPT1 | CRBN | HT-1080 | WO2022257897A1 | PGDB_A009419 | PGDB_C001816 | PGDB_AS000618 | View |
| Dmax | - | = | 63.6 | % | 10 uM | 20 h | CSNK1A1 | CRBN | HT-1080 | WO2022257897A1 | PGDB_A020997 | PGDB_C001816 | PGDB_AS000920 | View |
| DC50 | - | = | 1.11 | uM | - | — | CSNK1A1 | CRBN | HT-1080 | WO2022257897A1 | PGDB_A044226 | PGDB_C001816 | PGDB_AS001868 | View |
| Dmax | - | = | 56.5 | % | 10 uM | 20 h | CSNK1A1 | CRBN | HT-1080 | WO2022257897A1 | PGDB_A051310 | PGDB_C001816 | PGDB_AS000920 | View |
| Dmax | - | = | 15.3 | % | 10 uM | 20 h | GSPT1 | CRBN | HT-1080 | WO2022257897A1 | PGDB_A057561 | PGDB_C001816 | PGDB_AS000618 | View |
| DC50 | - | = | 0.0937 | uM | - | — | CSNK1A1 | CRBN | HT-1080 | WO2022257897A1 | PGDB_A070301 | PGDB_C001816 | PGDB_AS001868 | View |