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Compound
PGDB_C001844
6 activity records1 related patents
2D structure
O=C1CC[C@H](N2Cc3cc(C(=O)N[C@H](c4ccc(F)cc4)C4CCCC4)ccc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dmax | - | = | 29 | % | 10 uM | 20 h | GSPT1 | CRBN | HT-1080 | WO2022257897A1 | PGDB_A013401 | PGDB_C001844 | PGDB_AS000618 | View |
| DC50 | - | < | 0.0471 | uM | - | — | CSNK1A1 | CRBN | HT-1080 | WO2022257897A1 | PGDB_A015598 | PGDB_C001844 | PGDB_AS001868 | View |
| Dmax | - | = | 49 | % | 10 uM | 20 h | CSNK1A1 | CRBN | HT-1080 | WO2022257897A1 | PGDB_A022788 | PGDB_C001844 | PGDB_AS000920 | View |
| Dmax | - | = | 27.4 | % | 10 uM | 20 h | GSPT1 | CRBN | HT-1080 | WO2022257897A1 | PGDB_A049839 | PGDB_C001844 | PGDB_AS000618 | View |
| Dmax | - | = | 72.2 | % | 10 uM | 20 h | CSNK1A1 | CRBN | HT-1080 | WO2022257897A1 | PGDB_A062071 | PGDB_C001844 | PGDB_AS000920 | View |
| DC50 | - | = | 0.0535 | uM | - | — | CSNK1A1 | CRBN | HT-1080 | WO2022257897A1 | PGDB_A068274 | PGDB_C001844 | PGDB_AS001868 | View |