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Compound
PGDB_C002518
4 activity records1 related patents
2D structure
O=C1CCC(N2Cc3cc(CN4CCN(Cc5ccc(-c6ccc(Cl)cn6)cc5)CC4)ccc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | > | 50 | % | Concentration context: 500 nM | 24 h | IKZF1 | - | - | WO2024032689A1 | PGDB_A018625 | PGDB_C002518 | PGDB_AS002239 | View |
| % Degradation | - | < | 50 | % | Concentration context: 500 nM | 24 h | GSPT1 | - | - | WO2024032689A1 | PGDB_A028076 | PGDB_C002518 | PGDB_AS000668 | View |
| % Degradation | - | < | 50 | % | Concentration context: 500 nM | 24 h | IKZF3 | - | - | WO2024032689A1 | PGDB_A043717 | PGDB_C002518 | PGDB_AS000176 | View |
| IC50 | - | = | 500-1000 | nM | - | — | - | - | MM.1S | WO2024032689A1 | PGDB_A065141 | PGDB_C002518 | PGDB_AS001703 | View |