PatGlueDB | Molecular Glue Patent Bioactivity Database

Assay context summary

Assay context

138 activity records

Assay family% Degradation

Systemcell_based

Readout% Degradation

TargetIKZF1

E3Not specified

TechnologyWestern_blot

Detection targetprotein_degradation

Activity compounds and values

Activity records

138 records

Metric	Control	Relation	Value	Unit	Concentration	Time	Target	E3	Cell line	Patent	Record ID	Compound	Assay	Details
% Degradation	-	>	50	%	Concentration context: 500 nM	24 h	IKZF1	-	-	WO2024032689A1	PGDB_A007712	PGDB_C002556	PGDB_AS002239	View
% Degradation	-	>	50	%	Concentration context: 500 nM	24 h	IKZF1	-	-	WO2024032689A1	PGDB_A007764	PGDB_C002563	PGDB_AS002239	View
% Degradation	-	<	50	%	Concentration context: 500 nM	24 h	IKZF1	-	-	WO2024032689A1	PGDB_A008041	PGDB_C002601	PGDB_AS002239	View
% Degradation	-	>	50	%	Concentration context: 500 nM	24 h	IKZF1	-	-	WO2024032689A1	PGDB_A009533	PGDB_C002487	PGDB_AS002239	View
% Degradation	-	>	50	%	Concentration context: 500 nM	24 h	IKZF1	-	-	WO2024032689A1	PGDB_A010024	PGDB_C002616	PGDB_AS002239	View
% Degradation	-	<	50	%	Concentration context: 500 nM	24 h	IKZF1	-	-	WO2024032689A1	PGDB_A010186	PGDB_C002680	PGDB_AS002239	View
% Degradation	-	<	50	%	Concentration context: 500 nM	24 h	IKZF1	-	-	WO2024032689A1	PGDB_A011166	PGDB_C002645	PGDB_AS002239	View
% Degradation	-	>	50	%	Concentration context: 500 nM	24 h	IKZF1	-	-	WO2024032689A1	PGDB_A011965	PGDB_C002541	PGDB_AS002239	View
% Degradation	-	<	50	%	Concentration context: 500 nM	24 h	IKZF1	-	-	WO2024032689A1	PGDB_A012660	PGDB_C002744	PGDB_AS002239	View
% Degradation	-	<	50	%	Concentration context: 500 nM	24 h	IKZF1	-	-	WO2024032689A1	PGDB_A013434	PGDB_C002497	PGDB_AS002239	View
% Degradation	-	>	50	%	Concentration context: 500 nM	24 h	IKZF1	-	-	WO2024032689A1	PGDB_A014315	PGDB_C002492	PGDB_AS002239	View
% Degradation	-	<	50	%	Concentration context: 500 nM	24 h	IKZF1	-	-	WO2024032689A1	PGDB_A014947	PGDB_C002540	PGDB_AS002239	View
% Degradation	-	<	50	%	Concentration context: 500 nM	24 h	IKZF1	-	-	WO2024032689A1	PGDB_A016521	PGDB_C002502	PGDB_AS002239	View
% Degradation	-	>	50	%	Concentration context: 500 nM	24 h	IKZF1	-	-	WO2024032689A1	PGDB_A017601	PGDB_C002593	PGDB_AS002239	View
% Degradation	-	>	50	%	Concentration context: 500 nM	24 h	IKZF1	-	-	WO2024032689A1	PGDB_A017608	PGDB_C002527	PGDB_AS002239	View
% Degradation	-	>	50	%	Concentration context: 500 nM	24 h	IKZF1	-	-	WO2024032689A1	PGDB_A018433	PGDB_C002552	PGDB_AS002239	View
% Degradation	-	>	50	%	Concentration context: 500 nM	24 h	IKZF1	-	-	WO2024032689A1	PGDB_A018625	PGDB_C002518	PGDB_AS002239	View
% Degradation	-	<	50	%	Concentration context: 500 nM	24 h	IKZF1	-	-	WO2024032689A1	PGDB_A019179	PGDB_C002784	PGDB_AS002239	View
% Degradation	-	<	50	%	Concentration context: 500 nM	24 h	IKZF1	-	-	WO2024032689A1	PGDB_A019558	PGDB_C002692	PGDB_AS002239	View
% Degradation	-	<	50	%	Concentration context: 500 nM	24 h	IKZF1	-	-	WO2024032689A1	PGDB_A019621	PGDB_C002633	PGDB_AS002239	View

Rows per pagePage 1 of 7 · 138 recordsGo to page