PatGlueDB | Molecular Glue Patent Bioactivity Database

Assay context summary

Assay context

138 activity records

Assay family% Degradation

Systemcell_based

Readout% Degradation

TargetGSPT1

E3Not specified

OrganismHomo sapiens

TechnologyWestern_blot

Detection targetprotein_degradation

Activity compounds and values

Activity records

138 records

Metric	Control	Relation	Value	Unit	Concentration	Time	Target	E3	Cell line	Patent	Record ID	Compound	Assay	Details
% Degradation	-	>	50	%	Concentration context: 500 nM	24 h	GSPT1	-	-	WO2024032689A1	PGDB_A009062	PGDB_C002587	PGDB_AS000668	View
% Degradation	-	>	50	%	Concentration context: 500 nM	24 h	GSPT1	-	-	WO2024032689A1	PGDB_A009150	PGDB_C002535	PGDB_AS000668	View
% Degradation	-	>	50	%	Concentration context: 500 nM	24 h	GSPT1	-	-	WO2024032689A1	PGDB_A009446	PGDB_C002766	PGDB_AS000668	View
% Degradation	-	>	50	%	Concentration context: 500 nM	24 h	GSPT1	-	-	WO2024032689A1	PGDB_A010048	PGDB_C002499	PGDB_AS000668	View
% Degradation	-	>	50	%	Concentration context: 500 nM	24 h	GSPT1	-	-	WO2024032689A1	PGDB_A010064	PGDB_C002559	PGDB_AS000668	View
% Degradation	-	>	50	%	Concentration context: 500 nM	24 h	GSPT1	-	-	WO2024032689A1	PGDB_A010535	PGDB_C002550	PGDB_AS000668	View
% Degradation	-	>	50	%	Concentration context: 500 nM	24 h	GSPT1	-	-	WO2024032689A1	PGDB_A011777	PGDB_C002539	PGDB_AS000668	View
% Degradation	-	>	50	%	Concentration context: 500 nM	24 h	GSPT1	-	-	WO2024032689A1	PGDB_A012604	PGDB_C002698	PGDB_AS000668	View
% Degradation	-	<	50	%	Concentration context: 500 nM	24 h	GSPT1	-	-	WO2024032689A1	PGDB_A013925	PGDB_C002513	PGDB_AS000668	View
% Degradation	-	<	50	%	Concentration context: 500 nM	24 h	GSPT1	-	-	WO2024032689A1	PGDB_A014251	PGDB_C002511	PGDB_AS000668	View
% Degradation	-	>	50	%	Concentration context: 500 nM	24 h	GSPT1	-	-	WO2024032689A1	PGDB_A014999	PGDB_C002592	PGDB_AS000668	View
% Degradation	-	>	50	%	Concentration context: 500 nM	24 h	GSPT1	-	-	WO2024032689A1	PGDB_A015266	PGDB_C002547	PGDB_AS000668	View
% Degradation	-	<	50	%	Concentration context: 500 nM	24 h	GSPT1	-	-	WO2024032689A1	PGDB_A015401	PGDB_C002540	PGDB_AS000668	View
% Degradation	-	<	50	%	Concentration context: 500 nM	24 h	GSPT1	-	-	WO2024032689A1	PGDB_A015630	PGDB_C002509	PGDB_AS000668	View
% Degradation	-	>	50	%	Concentration context: 500 nM	24 h	GSPT1	-	-	WO2024032689A1	PGDB_A016713	PGDB_C002489	PGDB_AS000668	View
% Degradation	-	>	50	%	Concentration context: 500 nM	24 h	GSPT1	-	-	WO2024032689A1	PGDB_A016779	PGDB_C002579	PGDB_AS000668	View
% Degradation	-	<	50	%	Concentration context: 500 nM	24 h	GSPT1	-	-	WO2024032689A1	PGDB_A017050	PGDB_C002656	PGDB_AS000668	View
% Degradation	-	<	50	%	Concentration context: 500 nM	24 h	GSPT1	-	-	WO2024032689A1	PGDB_A017159	PGDB_C002527	PGDB_AS000668	View
% Degradation	-	>	50	%	Concentration context: 500 nM	24 h	GSPT1	-	-	WO2024032689A1	PGDB_A017248	PGDB_C002672	PGDB_AS000668	View
% Degradation	-	<	50	%	Concentration context: 500 nM	24 h	GSPT1	-	-	WO2024032689A1	PGDB_A018346	PGDB_C002738	PGDB_AS000668	View

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