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O=C1CCC(N2C(=O)c3ccc(N4CCC(CN5CCCN(c6cccc(-c7cnccc7Cl)c6)C5=O)CC4)cc3C2=O)C(=O)N1| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | = | 30 | % | 0.1 uM | 2 h | GSPT1 | - | HL-60 | WO2024073871A1 | PGDB_A017711 | PGDB_C002852 | PGDB_AS000569 | View | |
| IC50 | - | = | 234 | nM | - | — | GSPT1 | - | HL-60 | WO2024073871A1 | PGDB_A058400 | PGDB_C002852 | PGDB_AS000219 | View | |
| % Degradation | - | = | 48 | % | 1 uM | 2 h | GSPT1 | - | HL-60 | WO2024073871A1 | PGDB_A068993 | PGDB_C002852 | PGDB_AS001173 | View |