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Compound
PGDB_C002877
3 activity records1 related patents
2D structure
CCc1c[nH]c2ncc(-c3cccc(N4CCCN(CCC5CN(c6ccc7c(c6)C(=O)N(C6CCC(=O)NC6=O)C7=O)C5)C4=O)c3)c(Cl)c12Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 9.2 | nM | - | — | GSPT1 | - | HL-60 | WO2024073871A1 | PGDB_A010092 | PGDB_C002877 | PGDB_AS000219 | View |
| % Degradation | - | = | 95 | % | 1 uM | 2 h | GSPT1 | - | HL-60 | WO2024073871A1 | PGDB_A022297 | PGDB_C002877 | PGDB_AS001173 | View |
| % Degradation | - | = | 86 | % | 0.1 uM | 2 h | GSPT1 | - | HL-60 | WO2024073871A1 | PGDB_A070578 | PGDB_C002877 | PGDB_AS000569 | View |