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O=C1CCC(N2Cc3cc(Cn4cc(Nc5ccc(F)c(Cl)c5)nn4)ccc3C2=O)C(=O)N1| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| GI50 | - | = | 10 | nM | - | — | GSPT1 | - | NCI-H1155 | WO2024222614A1 | PGDB_A017336 | PGDB_C003207 | PGDB_AS000187 | View | |
| Dmax | - | = | 108 | % | - | 4 h | GSPT1 | - | NB4 | WO2024222614A1 | PGDB_A027329 | PGDB_C003207 | PGDB_AS000251 | View | |
| DC50 | - | = | 2.6 | nM | - | — | GSPT1 | - | NB4 | WO2024222614A1 | PGDB_A067222 | PGDB_C003207 | PGDB_AS001663 | View |